If you are looking for MLB picks, predictions and best bets for today’s San Francisco Giants vs Chicago Cubs matchup, we have you covered! Our MLB handicapping experts discuss the spread and total from a sports betting perspective, sharing their picks and predictions vs the current odds.
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San Francisco Giants vs. Chicago Cubs – May 5, 2025
📍 Location: Wrigley Field, Chicago, IL
🕖 First Pitch: 6:40 PM CT / 7:40 PM ET
📺 Watch Live: Marquee Sports Network (Chicago), NBC Sports Bay Area (San Francisco), or stream via MLB.TV.
📊 Game Odds (as of May 5)
Spread: Giants +1.5 (-176) | Cubs -1.5 (+146)
Moneyline: Giants +124 | Cubs -149
Over/Under: 7.5 runs
🧢 Team Hashtags
San Francisco Giants: #SFGiants
Chicago Cubs: #YouHaveToSeeIt
🔍 Team Highlights
San Francisco Giants
Current Record: 22–13, 3rd in NL West
Starting Pitcher: Landen Roupp (0–0, 0.00 ERA)
Streaming Update: Giants fans can now stream games via Peacock with an additional subscription, enhancing accessibility for those without traditional cable.
Chicago Cubs
Current Record: 21–14, 1st in NL Central
Starting Pitcher: Matthew Boyd (0–0, 0.00 ERA)
Injury Report: Outfielder Seiya Suzuki was recently scratched from the lineup due to right wrist discomfort.
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